How many times have you written a statement like this?
 
if ( (myString != null) && (myString != string.Empty) )
 
Often as a developer you have to check for both null and empty.  But now thanks to the new property IsNullOrEmpty() on the String object, you can check for both null or empty at the same time.  Just think of how much code you won't have to write now.
 
The above line would look like this:
 
if (String.IsNullOrEmpty(myString))
 
That is so much easier.

Read the complete post at http://www.dotnettipoftheday.com/blog.aspx?id=222